湖北某地区农村人群2型糖尿病及糖尿病前期横断面调查

摘要

Objective To examine the prevalence and risk factors of type 2 diabetes mellitus (T2DM ) and prediabetes in a rural population in Hubei province.Methods Random sampling method was used to recruit 10 800 rural residents aged over 40 years for this cross-sectional study.All subjects completed the questionnaire and underwent the physical examination.Fasting and postprandial 2 h blood samples were obtained for the biochemical tests.An oral glucose-tolerance test (75g OGTT ) was used to diagnose T2DM.Results ①The prevalence of T2DM was 9.99% in the cohort of rural population ,10.09% in males and 9.93% in females.The prevalence of prediabetes was 18.4% in this population ,18.8% in males and 18.1% in females ,re-spectively.②The prevalence of T2DM increased with age in both genders.The prevalence of T2DM was highest in over 70 years group. ③The prevalence of prediabetes was highest in 50-59 years group in males ,and over 70 years group in females. ④Multivariate analysis showed that age ,hypertension ,pulse ,waist height ratio (WHTR) ,waist hip ratio (WHR) ,body mass in-dex (BMI) ,drinking habit ,triglyceride (TG) ,total cholesterol (TC) were the risk factors of T2DM and prediabetes.Among these risk factors ,the increased pulse was positively correlated with T 2DM and prediabetes (OR=1.34 ,95% CI :1.25-1.44 ;OR=1.30 ,95% CI :1.23-1.37).Conclusion The prevalence of T2DM and prediabetes in rural populations in Hubei prov-ince is higher than the national level.Measures should be taken to strengthen the prevention ,treatment and education of T2DM and prediabetes in rural populations.%目的：了解湖北省农村人群2型糖尿病（T2DM ）和糖尿病（DM ）前期患病率及其高危因素。方法采用随机抽样方法，选取湖北省10800名40岁以上乡镇居民（天门市）进行横断面调查。对所有研究对象行问卷调查和常规体格检查，采用OGTT诊断T2DM ，留取空腹和餐后2 h静脉血进行相关生化检查。结果①湖北省乡镇居民（天门市） T2DM总患病率为9.99％，男性为10.09％，女性为9.93％。DM 前期患病率为18.4％，男性18.8％，女性18.1％。②男性和女性T2DM的患病率均随着年龄的增长而增加，70岁以上人群患病率达到最高。③男性的DM 前期患病率在50～59岁之间最高，女性在70岁以上最高。④多元Logistic回归分析显示年龄、血压、脉搏、腰围身高比（WHTR）、腰臀比（WHR）、体重身高指数（BMI）、饮酒史、甘油三酯（TG）、总胆固醇（TC）均为T2DM和DM 前期的高危因素，其中脉搏增快显著增加T2DM 和DM前期患病风险（分别为 OR＝1.34，95％ CI 1.25～1.44；OR＝1.30，95％ CI 1.23～1.37）。结论湖北省农村人群（天门市）T2DM及DM 前期的患病率较高，均高于全国DM患病率普查水平，应采取措施进一步加强对农村人群DM的防治和宣教。