声触诊组织定量在胰腺局灶性病变鉴别诊断中的初步应用

摘要

目的 探讨声触诊组织定量(VTQ)鉴别胰腺局灶性病变应用价值.方法 对51例胰腺占位患者行VTQ检查,分别获取病灶剪切波速(LSWV)、相邻胰腺实质剪切波速(PswV)及剪切波速差值(DSWV)(DSWV=LSWV-PSWV),对照病理结果或临床诊断,评估LSWV、PSWV和DSWV在胰腺局灶性病变的鉴别诊断价值.结果 恶性组的LSWV和PSWV分别为(2.39±1.25) m/s(0.60～4.39 m/s)和(1.59±0.63) m/s (0.76 ～3.22 m/s);潜在恶性组的LSWV和PSWV分别为(1.92±1.07) m/s (0.79～4.00 m/s)和(1.43 ±0.41)m/s (0.80～2.23 m/s);良性组的LSWV和PSWV分别为(2.40±1.10) m/s (0.89～3.42 m/s)和(1.48±0.44) m/s (1.03～2.11 m/s);良、恶性组内LSWV和PSWV差异有统计学意义(P=0.029,P=0.005),潜在恶性组的LSWV和PSWV差异无统计学意义(P=0.087).LSWV、PSWV和DSWV在3组间差异无统计学意义(P =0.401,P=0.638,P=0.625).LSWV与病灶大小不相关(r=0.253,P＞0.05);LSWV与感兴趣区深度呈负相关(r=-0.413,P＜0.05).结论 利用VTQ鉴别诊断胰腺局灶性病变的价值有待进一步的研究.%Objective To explore the potential value of the virtual touch tissue quantification (VTQ) in the differential diagnosis of focal pancreatic lesions.Methods Totally 51 patients with focal pancreatic lesions underwent the quantitative analysis by VTQ.Based on the pathologic or clinical diagnosis,the VTQ values including lesional shear wave velocity (LSWV),parenchymal shear wave velocity (PSWV),and difference shear wave velocity (DSWV) (DSWV =LSWV-PSWV) were compared between the lesions and background parenchyma.Results The mean LSWV and PSWV were (2.39 ± 1.25) m/s (0.60-4.39 rm/s) and (1.59 ± 0.63) m/s (0.76-3.22m/s) in malignant group,(1.92 ±1.07) m/s (0.79-4.00 m/s) and (1.43 ±0.41) m/s(0.80-2.23 m/s) in potentially malignant group,and (2.40 ± 1.10) m/s (0.89-3.42 m/s) and (1.48 ± 0.44) m/s (1.03-2.11 m/s) in benign group.There were statistically significant difference between LSWV and PSWV in bengin and malignant group (P =0.029,P =0.005),while no statistical significance in potential malignant group (P =0.087).However,LSWV,PSWV,and DSWV showed no significant difference amnong these three groups (P =0.401,P =0.638,P =0.625,respectively).LSWV was not significantly associated with the tumor size (r =0.253,P ＞ 0.05) but had negative correlation with the depth of region of interest (r =-0.413,P ＜ 0.05).Conclusion VTQ may be valuable in the differential diagnosis of focal pancreatic lesions,although further research is still required.