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Imaging of turbid media using trajectory filter methods.

机译:使用轨迹过滤器方法对混浊介质进行成像。

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摘要

Optical imaging through biological tissues and other scattering media is challenging, as the scattered light creates an extremely high background noise level that makes it difficult to detect objects that are embedded within the media.;This thesis examines a relatively unexplored method of separating scattered light from unscattered light that has application to optical imaging through turbid media. The method creates an optical filter that blocks photons based upon their exit trajectory direction. Such a trajectory filter can be used with a collimated beam that transmissively illuminates a scattering medium to create an imaging system in which a shadowgram is formed from those photons that pass through the filter and have a trajectory close to that of the collimated beam. Experiments have shown that such a system is effective up to measured optical depths of 18 to 21 and scattering ratios of 108 to 109 using both coherent and incoherent sources.;A micromachined linear array of 50 mum x 10 mm collimating holes was developed earlier as a photon trajectory filter and was used to successfully image through media in which the ratio of scattered to unscattered light is extremely high (>107). These results are much better than simple theory would predict. This thesis provides a theoretical basis for the trajectory filter system to allow its performance to be characterized and compared against other optical imaging methods, such as time-domain imaging. Using Monte Carlo simulations, it is found that the trajectory filter method is more effective than pathlength-based methods for imaging through turbid media with moderate levels of scattering, up to ~20 optical depths, and that it can be combined with other imaging methods to further improve contrast.;Advantages of the trajectory filter method include coherence and wavelength invariance and the ability to perform either wide beam, full-field or narrow beam, scanned imaging. Experimental results are presented for laser and incoherent beams using two types of trajectory filters: spatiofrequency and linear collimating hole array. It is found that the trajectory filter method offers a viable means of transmissively imaging through moderately scattering media at optical and near infrared wavelengths.;Keywords: Turbid media, Multiple scattering, Optical tomography, Tissue optics, Collimating optics.
机译:通过生物组织和其他散射介质进行光学成像具有挑战性,因为散射光会产生极高的背景噪声水平,这使得很难检测到嵌入在介质中的物体。未散射的光通过混浊的介质应用于光学成像。该方法创建了一个基于光子的出口轨迹方向来阻挡光子的滤光器。这样的轨迹滤波器可以与准直光束一起使用,该准直光束透射地照射散射介质以创建成像系统,在该成像系统中,通过穿过滤波器并且具有接近准直光束的轨迹的那些光子形成了阴影图。实验表明,使用相干光源和非相干光源,该系统在测得的18至21的光学深度和108至109的散射比下均有效。;早先开发了一种50毫米x 10毫米准直孔的微机械线性阵列光子轨迹过滤器,用于成功通过散射光与未散射光之比非常高(> 107)的介质成像。这些结果比简单的理论所预测的要好得多。本论文为轨迹滤波系统的性能表征和与时域成像等其他光学成像方法的比较提供了理论依据。使用蒙特卡洛模拟,发现通过基于中等长度散射,最大光学深度约为20的混浊介质成像,轨迹滤波方法比基于路径长度的方法更有效,并且可以与其他成像方法结合使用轨迹滤波器方法的优点包括相干性和波长不变性,以及执行宽光束,全场或窄光束扫描成像的能力。提出了使用两种类型的轨迹滤波器对激光光束和非相干光束进行实验的结果:空间频率和线性准直孔阵列。发现轨迹滤光片法提供了一种可行的手段,可以通过在光学和近红外波长的中等散射介质透射成像。关键词:混浊介质,多次散射,光学层析成像,组织光学,准直光学。

著录项

  • 作者

    Pfeiffer, Nicholas.;

  • 作者单位

    Simon Fraser University (Canada).;

  • 授予单位 Simon Fraser University (Canada).;
  • 学科 Physics Optics.;Engineering Electronics and Electrical.
  • 学位 Ph.D.
  • 年度 2009
  • 页码 390 p.
  • 总页数 390
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 能源与动力工程;
  • 关键词

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