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A study of the aorta rupture under pressure loading.

机译:压力负荷下主动脉破裂的研究。

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Rupture of the thoracic aorta accounts for nearly 20% of the fatalities from automobile crashes. The mechanisms of aorta rupture, however, remain a mystery due to the complexity of the connections, movements and the contacts among internal organs during the impact event. Although several hypotheses of aortic rupture mechanisms are presented in the literature, none has been validated owing to the difficulty of observing the aortic response and failure experimentally. One of the hypotheses is that sharp pressure increase cause aorta rupture. This dissertation is carried out to study aorta ruptures under pressure loading.; This dissertation constructed a finite element model of the aorta, investigated and applied the advanced technique of coupling Lagrangian and Eulerian finite element methods, developed a Pseudo-Elastic material model and integrated the material model into LS-DYNA3D, a widely used commercial finite element code. In addition, this dissertation analyzed the effect of aortic cross-section shape on the stress distribution.; Prior to implementation of the aorta structure model and material model, an excised aorta test was simulated. An inverse method was applied: the material parameter optimizations were conducted until general agreement was obtained between the simulation and the experiments.; Upon successful development of an isolated finite element model of aorta and a material model with failure criterion, the aorta model was further validated with the tests performed on in situ cadaveric aortas. The pressure increasing mechanism is thereafter investigated and it is found that the pressure itself was not enough to introduce aorta ruptures at 1000 mmHg level.; Finally, an elliptic aorta arch model was developed. An analytical study was conducted based on this model. The different shapes of aortic cross-section were investigated. It was found that the shape of the aortic cross-section dramatically affected the stress distribution. For a certain arch structure, the longitudinal stress might be greater than the circumferential stress, so the rupture occurs in the transverse direction. This analytical study explains the observed rupture direction.; The significant advance represented by this dissertation is the construction of a detailed human aorta finite element model with failure criterion that can effectively predict human aortic injury. It is a large step in the construction of an integral finite element model of a human body to aid in the design of more effective equipment to protect humans from potentially fatal injuries.; An additional contribution of this research is that the pressure alone is not enough to rupture the aorta at 1000 mmHg. The dynamic interaction between fluid and aortic wall, however, can cause aorta rupture at a relatively low-pressure level.
机译:胸主动脉破裂占车祸死亡人数的近20%。然而,由于撞击事件期间内部器官之间的连接,运动和接触的复杂性,主动脉破裂的机制仍然是个谜。尽管在文献中提出了几种关于主动脉破裂机制的假说,但由于难以观察到实验性的主动脉反应和衰竭,因此尚未得到验证。假设之一是急剧的压力增加会导致主动脉破裂。本文旨在研究压力负荷下的主动脉破裂。本文构建了主动脉的有限元模型,研究并应用了拉格朗日和欧拉有限元方法耦合的先进技术,开发了一种伪弹性材料模型,并将该模型集成到广泛使用的商业有限元代码LS-DYNA3D中。 。此外,本文分析了主动脉横截面形状对应力分布的影响。在实施主动脉结构模型和材料模型之前,对切除的主动脉测试进行了模拟。应用了一种相反的方法:进行材料参数优化,直到在仿真和实验之间达成总体协议为止。成功开发了孤立的主动脉有限元模型和具有破坏准则的材料模型后,通过对原位尸体主动脉进行的测试进一步验证了主动脉模型。此后研究了压力升高的机理,发现压力本身不足以在1000mmHg的水平上引起主动脉破裂。最后,建立了椭圆主动脉弓模型。基于该模型进行了分析研究。研究了主动脉横截面的不同形状。发现主动脉横截面的形状显着影响应力分布。对于某些拱形结构,纵向应力可能大于周向应力,因此破裂发生在横向。该分析研究解释了观察到的破裂方向。本文所代表的重大进展是建立了具有失效判据的详细人主动脉有限元模型,该模型可以有效预测人主动脉损伤。这是构建人体整体有限元模型的一大步骤,有助于设计更有效的设备来保护人类免受潜在的致命伤害。这项研究的另一个贡献是,单独的压力不足以使1000 mmHg的主动脉破裂。然而,流体与主动脉壁之间的动态相互作用会在相对较低的压力水平下引起主动脉破裂。

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