Regu-MateRTM (altrenogest) Management Practices and Potential for Exposure in Equine Care Givers.

摘要

Regu-Mate, the synthetic progesterone altrenogest, is used to control estrus in horses. Equine caregivers handling Regu-Mate may be exposed through accidental exposure or inadequate safety procedures. This exposure can result in adverse health effects including menstrual cycle changes, uterine/abdominal cramping, headaches and prolonged pregnancy. Surveys asked equine caregivers about Regu-Mate handling procedures, skin exposure to the drug, symptoms associated with exposure to the drug, and general background information. I analyzed results through descriptive statistics. Most respondents do not take sufficient safety precautions when handling Regu-Mate. Respondents most commonly use rubber/latex gloves or do not wear gloves when handling the drug and/or use a non-locking syringe to withdraw the medication. Respondents become complacent, taking fewer precautions the longer and more often they handle Regu-Mate. I developed a risk communication program that outlines the important safe handling discussion topics between veterinarians and clients and recommends a periodic check-in to evaluate a facility's procedures.