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Complexities for the design of self-assembly systems.

机译:自组装系统设计的复杂性。

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Self-assembly is the process by which objects autonomously assemble into complexes. It is believed that self-assembly technology will ultimately permit the precise fabrication of complex nanostructures. Of particular interest are self-assembly systems that are highly programmable. That is, we can view a self-assembly system as analogous to a program, the process of self-assembly as computation, and the resultant structure or shape assembled as the output. In this context, we are interested in the design of compact systems for the efficient assembly of desired target structures.; In this dissertation I present theoretical work in the area of self-assembly, focusing primarily on DNA self-assembly and the tile assembly model framework. I introduce a collection of new, natural models of self-assembly and show how these models affect the power of self-assembly. In doing so, we introduce new programming paradigms for self-assembly such as temperature programming . We further consider computational problems related to the design of self-assembly systems, including assembly verification and DNA strand design. For various formulations of these problems, we provide either efficient algorithmic solutions, or proofs of computational hardness.
机译:自组装是将对象自动组装为复合体的过程。人们相信,自组装技术将最终允许复杂纳米结构的精确制造。特别令人感兴趣的是高度可编程的自组装系统。也就是说,我们可以将自组装系统视为类似于程序的过程,将自组装过程视为计算,并将结果结构或形状组装为输出。在这种情况下,我们对紧凑型系统的设计感兴趣,以便有效地组装所需的目标结构。在这篇论文中,我介绍了自组装领域的理论工作,主要集中在DNA自组装和瓦片组装模型框架上。我介绍了一系列新的自然的自组装模型,并展示了这些模型如何影响自组装的力量。为此,我们引入了用于自组装的新编程范例,例如温度编程。我们进一步考虑与自组装系统设计有关的计算问题,包括组装验证和DNA链设计。对于这些问题的各种表述,我们提供了有效的算法解决方案或计算难度的证明。

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