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Design and fabrication of a refractometric chemical sensor using heterodyned widely tunable lasers.

机译:使用异质性广泛可调激光器的折光率化学传感器的设计和制造。

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摘要

In a time of increased concern over biological weapons and infectious diseases, a device which can rapidly and reliably determine whether a foreign substance is harmful or benign is strongly desired. Many of the most established technologies and processes for identifying a substance require treatment of the sample with fluorescent markers before testing; therefore, these devices have a slow response time and are inconvenient outside of a laboratory. Additionally, the quantification of pathogen concentration and detection of small amounts of a substance is less reliable if the human eye is the detector.; A new class of sensors uses optical techniques to detect the existence of a pathogen. These existing technologies for chemical index sensing require the use of external light sources, optics, and detectors. This requirement limits the portability and versatility of these devices and, therefore, restricts the incorporation of biosensors into field applications, doctors' offices, and consumers' homes. By leveraging the knowledge and sophistication of the telecommunications industry, integrated sensors can be fabricated which exhibit fast detection, a small footprint, and a good sensitivity to small concentration changes.; This thesis will discuss progress in using an established telecommunications platform for high sensitivity chemical sensing. The fabricated devices use a sensor design with frequency tunable lasers, heterodyne spectrometers, and an integrated waveguide photodetector. Slight changes in the refractive index surrounding the laser are measured through corresponding changes in the lasing frequency. By reducing the waveguide ridge width in one section of the laser, referred to as the sensing region, the transverse modal overlap increases by 10--20x, increasing the sensitivity by the same ratio. A frequency shift of 80 GHz/RIU was measured when temperature effects were removed. The long-term frequency stability of this sensor is as low as 1.6 MHz leading to a minimum detectable index difference of 2x10-5. This figure is comparable to many existing technologies which use external sources.
机译:在对生物武器和传染病的关注日益增加的时代,强烈期望一种能够快速且可靠地确定异物是有害还是良性的装置。用于鉴定物质的许多最成熟的技术和过程都需要在测试前用荧光标记物处理样品。因此,这些设备的响应时间很慢,并且在实验室之外很不方便。另外,如果人眼是检测器,则病原体浓度的定量和少量物质的检测就不太可靠。新型传感器使用光学技术来检测病原体的存在。这些用于化学指数感测的现有技术需要使用外部光源,光学器件和检测器。该要求限制了这些设备的便携性和多功能性,因此限制了将生物传感器结合到现场应用,医生办公室和消费者的家中。通过利用电信行业的知识和成熟度,可以制造出集成的传感器,该传感器显示出快速的检测,较小的占地面积以及对较小浓度变化的良好灵敏度。本文将讨论使用已建立的电信平台进行高灵敏度化学传感的进展。所制造的设备使用带有频率可调激光器,外差光谱仪和集成波导光电探测器的传感器设计。通过激光频率的相应变化来测量激光器周围折射率的轻微变化。通过减小激光在一个区域(称为感应区域)中的波导脊宽度,横向模态重叠将增加10--20倍,从而以相同的比率增加灵敏度。消除温度影响后,测得的频移为80 GHz / RIU。该传感器的长期频率稳定性低至1.6 MHz,因此可检测到的最小折射率差为2x10-5。这个数字可与使用外部资源的许多现有技术相媲美。

著录项

  • 作者

    Nolde, Jill Anitra.;

  • 作者单位

    University of California, Santa Barbara.;

  • 授予单位 University of California, Santa Barbara.;
  • 学科 Engineering Electronics and Electrical.
  • 学位 Ph.D.
  • 年度 2006
  • 页码 161 p.
  • 总页数 161
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 无线电电子学、电信技术;
  • 关键词

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