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Finite element modeling of human artery tissue with a nonlinear multi-mechanism inelastic material.

机译:用非线性多机制非弹性材料对人体动脉组织进行有限元建模。

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摘要

Due to limited experimental data and a lack of understanding of the underlying microstructural deformation mechanisms involved, modeling of material behavior of biomechanical tissues presents a rather formidable task. In this dissertation, a nonlinear multi-mechanism inelastic material model is formulated for modeling vascular tissue, collagen recruitment and elastin degradation. The model is implemented into the commercial finite element software package ANSYS with user programmable features. Although the idea of using several deformation mechanisms in the same material model is by no means novel, it is the first time such model is being implemented in a commercial finite element package and applied to a numerical study of physiological processes taking place inside the vascular walls. Two numerical examples are presented: a simulation of angioplasty procedure, and a finite element analysis of fusiform aneurysm development and growth. This is by far not the exhaustive list of possible applications of the developed material model; implementation in a commercial finite element code will help facilitate innovative developments, including new ways to surgically treat vascular disorders.
机译:由于有限的实验数据和对所涉及的潜在微结构变形机制的了解不足,生物力学组织的材料行为建模提出了一项相当艰巨的任务。本文建立了一种非线性多机制非弹性材料模型,用于建模血管组织,胶原蛋白募集和弹性蛋白降解。该模型已实施到具有用户可编程功能的商业有限元软件包ANSYS中。尽管在同一材料模型中使用几种变形机制的想法绝非新颖,但这是首次在商业有限元软件包中实现这种模型,并将其应用于对血管壁内部发生的生理过程进行数值研究。给出了两个数值示例:血管成形术的模拟,以及梭状动脉瘤的生长和生长的有限元分析。到目前为止,这还不是开发的材料模型可能应用的详尽清单。商业上有限元代码的实施将有助于促进创新发展,包括外科手术治疗血管疾病的新方法。

著录项

  • 作者

    Sidorov, Sergey.;

  • 作者单位

    University of Pittsburgh.;

  • 授予单位 University of Pittsburgh.;
  • 学科 Engineering Mechanical.
  • 学位 Ph.D.
  • 年度 2007
  • 页码 88 p.
  • 总页数 88
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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