声明
ABSTRACT
摘要
CONTENTS
ABBREVIATIONS
LIST OF FIGURES
LIST OF SCHEMES
LIST OF TABLES
Chapter 1：Introduction
1．1 Historical background of Polyurethane
1．2 Chemistry of Polyurethane
1．3 Types of polyurethanes
1．3．1 Polyurethane foams
1．3．2 Polyurethane hydrogels
1．3．3 Zwitterion Polyurethanes
1．3．4 Bio-based polyurethanes
1．3．5 Polyurethane Nanocomposites
1．4 Synthesis of polyurethane
1．4．1 Polyols
1．4．2 Natural Polyols
1．4．3 Isocyanates
1．4．4 Chain extenders
1．5 Applications of Polyurethane as a biomaterial
1．5．1 Antibacterial surfaces
1．5．2 Drug delivery vehicles
1．5．3 Stents
1．5．4 Tissue engineering scaffolds
1．5．5 Cardiac patches
1．5．6 PU coatings for breast implants
1．5．7 Surgical dressings and pressure sensitive adhesives
1．6 Aims and Objective
References
Chapter 2：Curcumin incorporated polyurethane urea elastomers with tenable thermo-mechanical properties
2．1 Introduction
2．2 Material and methods
2．2．1 Chemicals
2．2．2 Synthesis of curcumin polyurethane urea
2．2．3 Film casting
2．3 Characterizations
2．3．1 Spectroscopic Analysis
2．3．2 Tensile properties
2．3．3 Thermal analysis
2．3．4 Antimicrobial activity
2．3．5 Surface characterization
2．4 Results and Discussion
2．4．1 Structural confirmation
2．4．2 Mechanical Properties
2．4．3 Thermal Properties
2．4．4 Surface morphological analysis
2．4．5 Curcumin release
2．4．6 Antibacterial activity
2．5 Summary
References
Chapter 3：Thermo-mechanically improved curcumin and zwitterion incorporated polyurethane-urea elastomers
3．1 Introduction
3．2．Material and Methods
3．2．1．Chemicals
3．2．2 Synthesis of Z-diol
3．2．3 Synthesis of zwitterion and curcumin containing polyurethane urea
3．2．4 Film casting
3．3 Characterizations of Polyurethane-urea
3．3．1 Fourier Infrared Spectroscopy
3．3．2 1H NMR
3．3．3．Tensile properties
3．3．5．Surface characterizations
3．3．6．In vitro degradation
3．4 Results and discussion
3．4．1 Structure analysis
3．4．2 Tensile mechanical properties
3．4．3 Thermal properties
3．4．4 Contact angle and water adsorption
3．4．5 Surface morphology
3．4．6 In vitro degradation in PBS
3．5 Summary
References
Chapter 4：Synthesis of curcumin incorporated polyurethane／ZnO nanocomposites for biomedical applications
4．1 Introduction
4．2 Experimental section
4．2．1 Chemicals
4．2．2 Synthesis of curcumin incorporated PU／ZnO nanocomposites
4．3 Instruments and Testing Methods
4．4 Results and discussion
4．4．1 Structural characterization
4．4．2 Thermal Characterizations
4．4．3 Mechanical properties of PU nanocomposites
4．4．4 Cell Cytotoxicity Assay
4．4．5 Living and nonliving Cell Assay
4．4．6 SEM characterization of ZnCPU nanocomposites
4．4．7 Water adsorption
4．5 Summary
References
CONCLUSIONS
Future Plan
ACKNOWLEDGEMENTS
LIST OF PUBLICATIONS
Sayyed Asim Ali Shah(Author)
Supervisor Resume
