声明
ABSTRACT
ACKNOWLEDGEMENTS
TABLE OF CONTENTS
LIST OF FIGURES
LIST OF SCHEMES AND TABLES
ABBREVIATIONS
Chapter 1 General Introduction
1.1 Brief introduction of Biosensor
1.2 Nucleic acid based biosensor
1.2.1 General Introduction of fluorescence biosensor
1.2.2 Instrument based nucleic acid biosensor
1.2.3 Colorimetric nucleic acid biosensor
Chapter 2 Development of Saxitoxin sensor using inserted dyes
2.1 Introduction
2.2 Experimental
2.3 Results and Discussion
2.3.1 CD spectra analysis
2.3.2 ITC spectra analysis
2.3.3 Fluorescence spectra
2.4 Conclusion
Chapter 3 Construction of biosensors based on Quartz Crystal Microbalance-Dissipation platform
3.1 Adenosine detection based on QCM-D
3.1.1 Introduction
3.1.2.Experimental
3.1.3.Results and Discussion
3.1.4 Conclusion
3.2 Microcystein adsorption study using QCM-D
3.2.1 Introduction
3.2.2 Experimental
3.2.3 Results and Discussion
3.2.4 Conclusion
Chapter 4 Construction of biosensors based on AuNPs
4.1 Introduction
4.2 Experimental
4.3 Results and Discussion
4.3.1 Sensing Principle
4.3.2 Optimization of sensing conditions
4.3.3 The sensing range of poly (dA)15-AuNPs sensing system
4.3.4 Modulation of the sensing ranges
4.4 Conclusion
Chapter 5 Conclusion
Reference
Chapter 7 List of publications
摘要
绪论
结果与讨论
结论
中国科学技术大学;