超级伽玛刀治疗计划系统研究和开发

摘要

Along with the progess in radio-therapy equipment development as well as the medical imaging device,treatment planning system(TPS)was used widely and got incessant improvement in its performance due to the removation in computer hardware and software,and it is becoming the hotspot in the medical software develipment.From the beginning,1d,2d and2.5d,to now,3d TPS,the advanced comformal planning.IMRT and inverse planning technology have been applicated in TPS on many purpose,including conventional radiation treatment,MLC radio-therapy,X-knife,γ-knife and precision radio-therapy.Super Gamma System(SGS)is the new revolutionary product of OUR,which can do whole-body stereotactic radio-therapy and radiosurgery treatment of gamma ray,capable of treating head and body trauma with stereotactic radiosurgery,3Dconformal radio-therapy and IMRT.Some novel designing was produced in electric-mechanic structure,resulting in improving treatment efficiency,decreasing the cost and maintaining more easily.OUR-SGS treatment planning system (SGS-TPS)is a computerized tool assisting medical physicists,dosimetrists or doctors to do dose planning.After CT simulation,dose planning in the target and verification,the result can be drawn out and transferrde to the control system of SGS,thereafter,the treatment cna be performed.We analysed and moduled the software project with Object-Oriented Analysis and designing(OOAD)method,rational rose,programming with C++.And all the documentation were fulfilled according to FDA and SE.

目录

术语

ABSTRACT

第一章概述

1放射治疗

2立体定向放射治疗

(1)放射物理学要求

(2)放射生物学效应

(3)立体定向放射外科

(4)立体定向放射治疗

(5)SRS和SRT的比较

(6)伽玛刀

2放射治疗辅助设备

(1)医学影像设备

(2)定位框架和固定装置

3治疗计划系统(TPS)

(1）机器参数的输入

(2)病人资料和影象的输入

(3)图像处理

(4)三维重建

(5)规划工具

(6)剂量计算和显示

(7)计划评估

第二章国内外现状和发展趋势

1历史和现状

2国内外TPS产品

3评价TPS性能的标准

(1）一般特征

(2)外部束

(3)不规则野中点计算

(4)近距离治疗计划

4发展趋势

第三章超级伽玛刀特点

1概述

2创新特色

3 SGS的结构、原理

(1）射源装置

(2)屏蔽罐

(3)三维治疗床

(4)电气控制系统

(5)定位装置

(6)治疗计划系统

第四章SGS-TPS核心技术

1 CT模拟

(1） CT模拟与常规模拟的区别

(2)CT模拟的内容

(3)SGS定位方式和CT模拟

2 DRR(Digitally Reconstructed Radiographs)

(1)光线跟踪

(2)DRR的分辨率和精度

(3)CT值到X线衰减的转换

(4)DRR增强技术

3 DVH(Dose Volume Histogram)

4 DICOM3

5图像重建

6三维可视化

(1）图像配准

(2)边缘提取

(3)轮廓插值

(4)图像融合

(5)三维重建

7剂量计算

第五章SGS-TPS的开发

1概述

2 SGS-TPS开发的组织和项目管理

(1）设计需求分析

(2)风险分析和进度安排

(3)开发过程管理

2面向对象的分析和设计(OOAD)

3 ROSE工具

4技术可行性分析

5系统分析

(1)问题域描述

(2)USE CASE

(3)SCENARIO

(4)INTERACTIVE DIAGRAM

(5)CLASS DIAGRAM

(6)IMPLEMENTATION DIAGRAM

6设计需求

(1)项目概述

(2)具体需求

7软件需求

8编程开发

9测试

10软件模块介绍

(1）机器参数输入(Machine D缸a Ent叫)

(2)定位框架编辑器(Frame尉itor)

(3)胶片扫描输入(Film Scanner)

(4)配置工具(Configuration Tool)

第六章超伽剂量场的质量控制—胶片系统

1概述

2物理模型

(1)刻度片、剂量片、监测片和本底片

(2)胶片选择

2结果和讨论

第七章总结

参考文献：

致谢

博士期间发表的学术论文清单：

博士后期间发表的学术论文清单：

本人简历

放射治疗计划系统软件开发的项目管理

基于光线跟踪的数学影像重建技术

用于放射治疗计划的CT模拟技术研究

立体定向质子放射治疗计划系统