Nanostructured polymer thin films : Application to biosensors

摘要

The possibility to modify and control the surface wettability of different materials has attracted signicant scientic and technological interest. Particularly for biological systems (implantable microdevices in the body or microfluidic systems) the hydrophobic and hydrophilic nature of a surface plays a key role on the mediation of solute (e.g. protein) adsorption and cell adhesion [1,2]. Also, surface roughness may amplify hydrophobicity as observed with superhydrophobicity of self-cleaning surfaces like some plant leaves, e.g., lotus [3]. Such an effect can be desirable for channel flows since it can reduce resistance to the flow [4]. Moreover, the clinical use of so-called non-fouling surfaces requires the ability to effectively interface with the biological milieu in a non-immunogenic and stable manner [5].