Application of Captopril Self-assembled Monolayer on Gold Electrode as a Sensor for Pb(II)-sensing

摘要

Ministry of Education and Department of Chemistry, Fuzhou University, Fuzhou, 350002, China Fuzhou, 350002, China The lead poisoning is the most common disease of environment [1]. As a kind of accumulative poison, Lead is easily absorbed by the stomach and affects the metabolism of enzyme and cell through the blood circulation. Excessive intake of lead will seriously do harm to human health, especially to kids, and its main toxicity will cause anemia, nerve damage and kidney dysfunction. Fast detection of sub micro-level lead in environmental samples and biological samples is necessary for monitoring and researching the lead poisoning. Electrochemical stripping analysis techniques have been traditionally used for the determination of trace lead, and some electrodes have been reported, such as hanging mercury drop electrode (HMDE) [2], mercury-film [3], polymer-coated electrodes [4] and self-assembled monolayer modified gold electrode [5-6]. Some of mercury electrode based methods allow the concentrations of lead determined as low as 10-10 molL-1.However, to develop a new Pb sensor without mercury that is of high selectivity, reproduciblility and good stability is a general trend.