Surface Engineering with Thiol-Click Reactions

摘要

Thiol-click reactions have emerged as an invaluable synthetic tool for the preparation of functional polymeric materials and surfaces. This presentation will focus on our recent efforts to utilize a series of thiol "click" reactions, including the thiol-yne, thiol-ene, and thiol-isocyanate reactions for the fabrication of functional polymer surfaces. These reactions enable the rapid generation of a diverse library of functional surfaces, utilize a structurally diverse range of commercially available or easily attainable reagents and proceed rapidly to quantitative conversions under mild reaction conditions. In this work, we demonstrate thiol click reactions as a modular platform for the fabrication of highly functional, patterned, and multicomponent polymer brushes for a variety of applications including stimuli responsive and bio-related surfaces.