首页> 外文会议>Symposium on innovative polymers for controlled delivery: Abstract book. >CONTROLLED RELEASE OF BOVINE SERUM ALBUMIN FROM ELECTROSPUN FIBROUS MEMBRANES VIA AN IMPROVED EMULSION-CORE TECHNIQUE
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CONTROLLED RELEASE OF BOVINE SERUM ALBUMIN FROM ELECTROSPUN FIBROUS MEMBRANES VIA AN IMPROVED EMULSION-CORE TECHNIQUE

机译:通过改进的乳液核心技术从电纺纤维膜中控制释放牛血清白蛋白

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摘要

Bovine serum albumin (BSA), entrapped in a water-in-oil emulsion as the core, was encapsulated in the shell polymer via emulsion-core (EC) coaxial electrospinning. Fibrous membranes prepared via this improved electrospinning technique could successfully reduce the initial release of BSA. Additionally, the release rate could be tailored by changing the composition of poly(L-lactide-co-glycolide) in the core emulsion. The results showed that EC coaxial electrospinning performed better than conventional coaxial electrospinning with respect to protein delivery in tissue engineering.
机译:包埋在油包水乳液中作为核心的牛血清白蛋白(BSA)通过乳液核心(EC)同轴电纺丝被包裹在壳聚合物中。通过这种改进的静电纺丝技术制备的纤维膜可以成功减少BSA的初始释放。另外,可以通过改变核心乳液中聚(L-丙交酯-共-乙交酯)的组成来调整释放速率。结果表明,就组织工程中的蛋白质输送而言,EC同轴电纺比常规同轴电纺表现更好。

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