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首页> 外文会议>Symposium on innovative polymers for controlled delivery: Abstract book. >A NOVEL ORAL COLON-TARGETING DRUG DELIVERY SYSTEM BASED ON RESISTANT STARCH ACETATE
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A NOVEL ORAL COLON-TARGETING DRUG DELIVERY SYSTEM BASED ON RESISTANT STARCH ACETATE

机译：基于抗淀粉淀粉的新型口服结肠靶向药物输送系统

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摘要

Novel oral colon-targeting film-coated pellets based on resistant starch acetate (RSA) film were prepared and the effect of plasticizer content, film coating thickness, drug load and drug molecular weight on drug release was investigated. Desired colon-targeting and drug release properties can easily be obtained by adjusting the coating thickness as well as the plasticizer content of the RSA film. This suggested that RSA film coated-pellet is an excellent and potential oral colon targeting drug delivery system.
机译：制备了一种新型的基于抗性乙酸醋酸酯（RSA）薄膜的口服靶向结肠的薄膜包衣小丸，并研究了增塑剂含量，薄膜包衣厚度，载药量和药物分子量对药物释放的影响。通过调节RSA膜的涂层厚度和增塑剂含量，可以轻松获得所需的结肠靶向和药物释放特性。这表明RSA薄膜包衣小丸是一种出色的潜在口服结肠靶向药物递送系统。

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  • 来源
  • 会议地点 Suzhou(CN);Suzhou(CN)
  • 作者

    Ling Chen; Huayin Pu; Xiaoxi Li; Long Yu;

  • 作者单位

    Engineering Research Center of Starch Protein Processing, Ministry of Education, South China University of Technology, Guangzhou 510640, China;

    Engineering Research Center of Starch Protein Processing, Ministry of Education, South China University of Technology, Guangzhou 510640, China;

    Engineering Research Center of Starch Protein Processing, Ministry of Education, South China University of Technology, Guangzhou 510640, China;

    Engineering Research Center of Starch Protein Processing, Ministry of Education, South China University of Technology, Guangzhou 510640, China,Commonwealth Scientific and Industrial Research Organization, Materials Science and Engineering,Melbourne, Victoria 3169, Australia;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物材料学;生物材料学;
  • 关键词

    colon-targeting; resistant starch acetate; film-coated pellets; in vitro drug release;

    机译：结肠靶向；抗乙酸淀粉酯；薄膜包衣小丸；体外药物释放;

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