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A New Scheme for Time-Resolved Diffusing Wave Spectroscopy

机译:时间分辨扩散波谱的新方案

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Diffusing Wave Spectroscopy (DWS) consists in the measurement of temporal correlation of the electromagnetic field in the diffusion regime, allowing a scan of dynamical properties deep inside a medium. DWS is of special interest in biomedical optics, as it is sensitive to blood circulation in capillaries inside the tissue.rnHowever one main difficulty of this technique concerns data extraction which implies to perform an inverse problem taking into account the geometry and the optical coefficients of the medium. The use of time-resolved detection has been proved to be an efficient tool to discriminate the DWS information, but the photon path lengths were up to now limited to a few tens mean free paths.rnIn order to perform time-resolved DWS for much longer photon paths, we used a new method, based on the use of an interferometer and a wavelength modulated source. We have already demonstrated that this method, in addition to its lower cost, was very efficient to perform time-resolved measurements of the light scattered by a thick scattering medium. We will show in this poster some measurements performed by transillumination through a thick medium (4cm), opening the possibility of Time-Resolved DWS measurements in the human breast.
机译:扩散波谱(DWS)包括测量扩散状态下电磁场的时间相关性,从而可以扫描介质内部的动态特性。 DWS对生物医学光学特别感兴趣,因为它对组织内部毛细血管中的血液循环敏感。然而,该技术的一个主要困难涉及数据提取,这意味着要考虑到几何形状和光学系数来执行反问题。介质。事实证明,使用时间分辨检测是区分DWS信息的有效工具,但迄今为止,光子路径长度仅限于几十个平均自由程。光子路径,我们使用了一种基于干涉仪和波长调制光源的新方法。我们已经证明,该方法除成本较低外,还可以非常有效地对厚散射介质散射的光进行时间分辨测量。我们将在此海报中展示通过厚介质(4cm)进行透照进行的一些测量,这为在人类乳房中进行时间分辨DWS测量提供了可能性。

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