Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment

摘要

In conclusion, we have shown that photocrosslinkable HA, a natural and biocompatible polymer, can be easily integrated with existing microfabrication techniques to fabricate microstructures. The technique presented here has been shown to be useful for capturing cells inside HA microwells or for encapsulating cells directly within the HA gels. In both approaches, the cells remained viable and could be retrieved for future analysis, either through mechanical forces or enzymatic digestion of HA.