Targeted Drug Delivery with Magnetic Nanoparticles

摘要

It has been demonstrated that the PLGA coated drug loaded nanoparticles can deliver the model antibiotic, azithromycin, in a sustained manner. Further, PLGA coating makes the particles more biocompatible and it seems to be suitable for the magnetically targeted delivery system for cytotoxic cancer drugs. This system seems to be also suitable for sustained release of antibiotics, e.g azithromycin itself. With its biological half life of over 50 hours this could be also used for single dose antibiotic therapy.