3-D Visualization of Paclitaxel in Polymer Films by Coherent Anti-Stokes Raman Scattering Microscopy

摘要

CARS microscopy provided an excellent imaging tool to investigate drug distribution and release behavior in situ from a solid state polymer matrix. Drug release behavior from a polymer matrix was imaged in situ with 3D resolution using CARS microscopy. The unique ability of CARS microscopy to image drug molecules without labeling is extremely useful in the studies of various drug delivery systems and biomaterials.