Bone regeneration on nano-fibrous reverse solid freeform fabricated poly(L-lactic acid) scaffolds

摘要

By combining polymer phase separation with SFF, we have created a NF architecture capable of being produced with SFF manufacturing techniques which promotes bone tissue regeneration. In this study we have demonstrated increased differentiation and mineralization on NF scaffolds and the flexibility of the fabrication method to form complex forms. This technique holds great promise to create ideal scaffolds for bone tissue engineering.