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Motion control of Tetrahymena pyriformis cells with artificial magnetotaxis: Model Predictive Control (MPC) approach

机译:用人工趋磁法控制梨形四膜虫细胞的运动:模型预测控制(MPC)方法

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The use of live microbial cells as microscale robots is an attractive premise, primarily because they are easy to produce and to fuel. In this paper, we study the motion control of magnetotactic Tetrahymena pyriformis cells. Magnetotactic T. pyriformis is produced by introducing artificial magnetic dipole into the cells. Subsequently, they can be steered by using an external magnetic field. We observe that the external magnetic field can only be used to affect the swimming direction of the cells, while the swimming velocity depends largely on the cells' own propulsion. Feedback information for control is obtained from a computer vision system that tracks the cell. The contribution of this paper is twofold. First, we construct a discrete-time model for the cell dynamics that is based on first principle. Subsequently, we identify the model parameters using the Least Squares approach. Second, we formulate a model predictive approach for feedback control of magnetotactic T. pyriformis. Both the model fitness and the performance of the feedback controller are verified using experimental data.
机译:使用活微生物细胞作为微型机器人是一个有吸引力的前提,主要是因为它们易于生产和加燃料。在本文中,我们研究了趋磁性膜炎四膜虫细胞的运动控制。通过将人工磁偶极子引入细胞中来形成趋趋性拟南芥。随后,可以通过使用外部磁场来操纵它们。我们观察到,外部磁场只能用于影响细胞的游泳方向,而游泳速度在很大程度上取决于细胞自身的推进力。用于控制的反馈信息是从跟踪单元的计算机视觉系统获得的。本文的贡献是双重的。首先,我们基于第一个原理为细胞动力学构建离散时间模型。随后,我们使用最小二乘法确定模型参数。其次,我们制定了一种模型预测方法,用于对趋磁性T.formiformis的反馈控制。使用实验数据验证模型的适用性和反馈控制器的性能。

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