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On the Structure of Reconciliations

机译:关于和解的结构

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摘要

In this paper we present an extended model related to reconciliation concepts. It is based on gene duplications, gene losses and speciation events. We define an evolutionary scenario (called a DLS-tree) which informally can represent an evolution of genes in species. We are interested in all scenarios - not only parsimonious ones. We propose a system of rules for transforming the scenarios. We prove that the system is confluent, sound and strongly normalizing. We show that a scenario in normal form (i.e. non-reducible) is unique and minimal in the sense of the cost computed as the total number of gene duplications and losses. Moreover, we present a classification of the scenarios and analyze their hierarchy. Finally, we prove that the tree in normal form could be easily transformed into the reconciled tree in duplication-loss model. This solves some open problems stated in [13].
机译:在本文中,我们提出了与对帐概念相关的扩展模型。它基于基因重复,基因丢失和物种形成事件。我们定义了一个进化场景(称为DLS树),它可以非正式地代表物种中基因的进化。我们对所有场景都感兴趣-不仅是简约场景。我们提出了用于转换方案的规则系统。我们证明该系统是融合的,健全的并且高度规范化的。我们显示出正常形式(即不可还原)的情况是独特的,并且在以基因重复和损失总数计算的成本意义上来说是最小的。此外,我们提出了方案的分类并分析了它们的层次结构。最后,我们证明了正常形式的树在重复损失模型中可以轻松地转换为协调树。这解决了[13]中提到的一些开放问题。

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