Surfactant Free CO2-in-Water Emuision-templated Poly(vinyl alcohol) Hydrogels and Their Applications in Tissue Engineering

摘要

Polymerized high internal phase emulsions (polyHIPEs),with a highly porous and interconnected morphology,are materials prepared by polymerizing the continuous phase of an HIPE.And the cavity size of polyHIPEs is easily tunable by various means[1].Unfortunately,a large amount of organic solvents are used in the traditional HIPE.These problems can be overcame by templating supercritical CO2-in-water (C/W)emulsions.However,CO2 is feeble solvent and most of polymers and polar masses are difficult to dissolve;effective surfactants play an important role in the formation of C/W emulsions.The surfactants are usually non-degradable and difficult to be removed from the monoliths[2].