Phylogeny of medically important dematiaceous fungi based on rapd fingerprints and protein patterns by sds-page

摘要

Dematiaceous fungi (Dematiaceae) are a large and diverse group of hyphomycete that has typical morphology and is observed as asexual forms. They have b een isolated as saprobles, and a few of them may be pathogenic to human and animals. The most important pathogenic agents to human are Fonsecaea pedrosoi, Fonsecaea compacta, Phialopra verrucosa, Wangiella dermatitidis, Cladosporium carrionii and expophiala jeanselmei, which cause chromoblastomycosis, Phaeohyphomycosis, and eumycotic mycetoma. Over the past few decades the systematics, the nomencluature and the identification of Dematiacease have been confusing and controversial, and they are regarded as the most complicated and difficult in the field of medical mycology. The key is htat the phylogenetic relationships among this family is not well-understanding, and so the reliable, complete and accurate natural taxonomic system is not well established.