Fast Tools to Monitor Potential Dangerous Reactions

摘要

Differential scanning calorimetry provides insights into chemical reactions as reactionrnenthalpies and rates are easily gained. The resulting calorimetric information can be used tornidentify process parameters, assess chemical reaction hazards, and provide data that can be usedrnfor thermodynamic and kinetic calculations.rnAdvanced techniques such as model free kinetics enhance the performance of kineticrnevaluations from several DSC or TGA curves without selecting a defined reaction model. Therninvestigations can be extended to complex temperature programs such as a combination of dynamicrnand isothermal measurement used in chemical processes. This allows rate predictions forrnsituations not measured or not in the range of normal fast measurements. Using isothermal andrndynamic measurements at different heating rates, we studied standard chemical reactions andrncorrelated the predictions obtained by DSC and TGA with proof measurements.rnExamples of exothermic decomposition reactions were used to demonstrate how thernmodel free kinetics can be employed to study the potential risk in a process. Overlapping effectsrnsuch as evaporations can be avoided by using high pressure crucibles while the influence of pressurerncan be studied by pressure DSC.