Experimental research on LED light source used for ALA-PDT

摘要

A LED array is used as PDT light source in a photo-reaction chamber. The LED array is alterable in wavelength by replacing different LEDs, stable in output power, adjustable in power value and spot size; the geometry of the LED array is flat shape. Based on the experiment of ALA-PDT, we measured and analyzed the spectrum characteristics and output power of some different purple LEDs, selected one as PDT light source whose emission peak is near the absorption peak of the ALA. The experiment on HL60 tumor cells in vitro demonstrates our photo-reaction chamber has visible photodynamic effect on ALA-PDT.