Transient Analysis of Cooling of Biological Tissues Using Semi-Infinite Approximation

摘要

Thermal cooling of biological tissues due to flow of blood in micro-capillaries is useful for several biomedical applications. The objective of the present study is to develop a better qualitative and quantitative understanding of the thermal cooling due to interaction between the blood flow in capillaries and the tissue environment. Analytical expression for one-dimensional temperature distribution in biological tissue is reported without considering the bloodstream cooling. In this paper, an analytical modeling is reported to determine the transient temperature distribution inside a tissue due to flow of blood. The contact resistance between the tissues is neglected. Using the continuum approach the tissues are modeled as a single body and localized tissue is treated as a semi-infinite body. Finally the expression for heat flux is determined based on the transient temperature distribution.