Molecular Dynamics of Biomimetic Ionomers Studied by Dielectric Spectroscopy on the Nanometer Length Scale

摘要

Information about the dynamic molecular processes in materials is important for understanding the material's functionality in biotechnological applications, and in the present work we show the potential of dielectric spectroscopy in providing such information. In this study, dielectric spectroscopy is used to study the bulk properties of the phosphoryl choline (PC) functionalized poly (trimethylene carbonate) (PTMC), ionomer compared to the unfunctionalized PTMC_(diol). The data clearly shows the presence of the polar PC end groups and the diffusion constant of these moieties is calculated. This information indicates the ability of the material to function as a controlled drug release vehicle in which drug molecules are incorporated within the PC aggregates to create a drug reservoir in the material bulk.