Extracting quantitative biomechanical parameters for cartilage from second harmonic generation images

摘要

Cartilage from the medial femoral condyle of chicken was sectioned and imaged using second harmonic generation microscopy. Using image analysis techniques based on the Fourier transform we derived quantitative three-dimensional data of the fiber direction and dispersion of the collagen fiber network in the superficial layer. These data can be used directly in biomechanical models to enhance the fidelity of these models.