Combating Infectious Diseases with Computational Immunology

摘要

Computational immunology aims at investigation of the immunity with computer science, mathematics, physics or statistics. Immune simulator is one of the outputs of research in computational immunology. Development of immune simulator is derived from the analysis of application domain and design of simulator with particular conceptual modelling language. Conceptualization is then used for simulator programming. The paper reviews and compares the most cited approaches of conceptual modelling and computational models building.