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Predictive Analytics Based on Open Source Technologies for Acute Respiratory Distress Syndrome

机译:基于开源技术的急性呼吸窘迫综合征的预测分析

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The continuous growth of high volumes of biomedical data in healthcare generates significant challenges for their efficient management. This data requires efficient management and analysis in order to derive meaningful and actionable information. Especially in the current situation of the COVID-19 pandemic, complications that might occur after the onset of this disease are important. Such a complication is Acute Respiratory Distress Syndrome (ARDS), which is a serious respiratory condition with high mortality and associated morbidity. A large number of basic and clinical studies demonstrated that early diagnosis and intervention are keys to improve the survival rate of patients with ARDS. Therefore, there is a pressing need for the development and clinical testing of predictive models for ARDS events, which might improve the clinical diagnosis or the management of ARDS. In this paper, we focus on two distinct objectives; namely a) to design a scalable data science platform, built on open source technologies able to streamline the development of such models, and b) to exploit the platform using publicly available big datasets to develop such models. To this direction, we employ random forests and logistic regression algorithmic models for the early prediction and diagnosis of ARDS. Our approach achieves better results in all metrics, when compared to relevant published efforts using the MIMIC III dataset.
机译:医疗保健中的高卷生物医学数据的持续增长产生了高效管理的重大挑战。该数据需要有效的管理和分析,以推导出有意义和可操作的信息。特别是在Covid-19大流行的当前情况下,这种疾病发作后可能发生的并发症是重要的。这种并发症是急性呼吸窘迫综合征(ARDS),这是一种严重的呼吸状况,具有高死亡率和相关的发病率。大量基本和临床研究表明,早期诊断和干预是提高ARDS患者的存活率的键。因此,需要对ARDS事件的预测模型进行开发和临床测试,这可能改善临床诊断或ARDS的管理。在本文中,我们专注于两个不同的目标;即a)设计可扩展的数据科学平台,建立在能够简化此类模型的开发的开源技术上,B)利用公开的大数据集利用该平台来开发这些模型。在这个方向上,我们采用随机森林和逻辑回归算法模型,用于ARDS的早期预测和诊断。与使用模仿III数据集的相关公开工作相比,我们的方法在所有指标中实现了更好的结果。

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