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Breakthroughs of using Photodynamic Therapy and Gold Nanoparticles in Cancer Treatment

机译:光动力疗法和金纳米颗粒在癌症治疗中的突破

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The term “cancer” covers more than a hundred diseases that assign one trait: the abandoned growth of abnormal cells that abolish healthy tissues and have the potential to spread outside its site of origin. When a malignant tumor originates in the breast, it is called breast cancer. Gold nano particles display potential for both the imaging and cure of breast cancer. From a logistical standpoint, most breast tumors arise near the skin's surface, where they may possibly be extracted and handled despite the NIR laser's minimal tissue penetration. Photodynamic therapy is a fairly new treatment option for both cancer and non-cancer diseases that involves the activation of certain dyes with light in the existence of molecular oxygen (photosensitizers) that the target tissue has absorbed in a very selective manner. The combination of hyperthermia and photoelectric dose improvement of radiation therapy could be effectively treat superficial positioned inflammatory breast cancer sorrecurrence in the post-mastectomy chest wall. In this review paper, the novel work in photothermal therapy is debated, as well as the combined effects of gold nanoparticles and photothermal heating on breast cancer cells are studied in details.
机译:“癌症”一词涵盖了一百多种疾病,它们具有一个特征:异常细胞的废弃生长,这些细胞会破坏健康组织,并有可能在其起源地之外传播。当恶性肿瘤起源于乳腺时,它被称为乳腺癌。金纳米粒子在乳腺癌的成像和治疗方面都显示出潜力。从后勤角度来看,大多数乳腺肿瘤发生在皮肤表面附近,尽管近红外激光的组织穿透性很小,但它们可能在皮肤表面被提取和处理。光动力疗法是癌症和非癌症疾病的一种全新治疗选择,它涉及在目标组织以非常有选择性的方式吸收的分子氧(光敏剂)存在的情况下,用光激活某些染料。热疗和提高光电剂量的放射治疗相结合,可有效治疗乳腺癌术后胸壁浅表定位炎性复发。在这篇综述文章中,我们讨论了光热疗法方面的新工作,并详细研究了金纳米颗粒和光热加热对乳腺癌细胞的联合作用。

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