Potential of Andalas (Morus macroura Miq.) Ethanol Extract in Inhibiting the Microbial Growth

摘要

Andalas (Morus macroura Miq.) is a West Sumatra, Indonesia mascot plant. This plant is a Moraceae group, which is widely used traditionally as a medicinal plant. The purpose of this study was to determine the potential of Andalas ethanol extract in inhibiting the growth of pathogen microbes. Ethanol extraction was done to the roots and stems of Andalas. To see the optimum concentration of ethanol extracts of Andalas roots and stems in inhibiting test microbes, a completely randomized design (CRD) was used. The treatments given in this study were extract concentration of 3.12%, 6.25%, 12.50%, and 25%, respectively. Antimicrobial activity tests were carried out on test microbes (Staphylococcus aureus, Escherichia coli, and Candida albicans) using the paper disc diffusion method. The results showed that the optimum concentration of Andaleh root ethanol extract in inhibiting the growth of S. aureus and E. coli was at 12.5% and 3.125%. Meanwhile, the best concentration of ethanol extract of Andaleh stem in inhibiting the growth of S. aureus and E. coli was at 25%. There was no antimicrobial activity of the ethanol extract of Andaleh roots and stem against the growth of C. albicans.