Hydrolysis of a neutral hydrogel and biomolecule attachment to increase cell adhesion and migration

摘要

Tissue epikeratophakia is a surgical procedure where a processed human corneal tissue is implanted onto the surface of a recipient cornea for refractive correction. The procedure was originally described by Barraquer and clinicals trials were conducted in the United States under the tradename KeratoLens~(TM). The surgical procedure involves removal of the surface epithelium, creating a peripheral mid-depth pocket in the recipient cornea, and tucking in and suturing the periphery of the rehydrated tissue lens. After implantation the tissue graft must reepithelialize and clear before the final visual outcome can be determined.