The Use of Dithizone for Lead Analysis in Blush

摘要

Objectives: In this research, lead analysis was carried out on the blush cosmetic preparations using the UV-Vis Spectrophotometry method and dithizone complex. The purposes of this study are to determine lead levels in cosmetics blush preparations and to determine the safety of the blush preparations that are circulating concerning the provisions of BPOM The results obtained by the regression equation y = 7.895x + 0.0701 with a correlation coefficient of 0.9984; the detection limit was 0.00596 ppm and the limit of quantitation was 0.0198 ppm. Accuracy tests result the percent recovery of 80, 100, and 120% concentrations respectively 94.08; 97.86; and 98.77%. The results of consecutive precision tests are 0.9297; 0.5098; 0.3351; 0.1565; and 0.1842%. The blush sample preparation process is carried out with the dry destruction method, which goes through the drying and graying stages. The destroyed ash was added with 6 M hydrochloric acid, then drying again. The drying product was dissolved with 0.1 M nitric acid. Dry destruction digestion sample solution was used for the analysis of lead content in the blush sample. The test result showed that the lead content in the sample was 0.0599 ppm. Based on the BPOM's Head Regulation No.17 of 2014 on lead contamination in cosmetics must not exceed 20 ppm, so the blush cosmetic is still below the threshold set by BPOM and still safe to use.