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Research on Spectrum Analysis of Photoacoustic Signal Based on COMSOL Platform

机译:基于COMSOL平台的光声信号频谱分析研究

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The study of the relationship between the spectral characteristics of the photoacoustic signal and the shape and size of the absorber has important practical significance for image reconstruction. Using the commercial finite element simulation software COMSOL Multiphysics, a two-dimensional simulation model based on finite element was designed, which studied the relationship between the spectral characteristics of the photoacoustic signal and the shape and size of the absorber. In this study, the model consists of three parts: 1) water layer; 2) short pulse laser source (wavelength of 840nm); 3) gastric tumor tissue. The laser point source is located in the middle of the upper water layer. Simulate the propagation of light in the water layer by solving the diffusion equation. The temperature changes in biological tissues are obtained by solving the biothermal equation. When the absorber is irradiated by Gaussian pulses, due to the extremely short time, the absorber can be regarded as adiabatic expansion after absorbing energy, thereby generating ultrasonic waves. Using the finite element analysis method, the complex situation of photoacoustic imaging is transformed into the coupling of multiple physical fields and the numerical calculation of partial differential equations to obtain the photoacoustic signal. Fitting the simulation results shows that the spectral characteristics of the photoacoustic signal change regularly with the size of the absorber. The size of the absorber obtained in this paper has a power function relationship with the spectral intercept. The larger the size, the larger the spectral intercept, and the growth rate increases with the increase of the size. The size of the absorber and the spectral slope also have a power function relationship. The slope of the large spectrum is smaller, and the rate of change of the slope decreases as the size increases. At the same time, analyzing the photoacoustic spectrum of absorbers of different shapes also shows that absorbers of different shapes have their own characteristics. This research is helpful to understand the relationship between spectral characteristics and the shape and size of the absorber, and has certain theoretical guiding significance for image reconstruction.
机译:光声信号光谱特性与吸收器的形状和尺寸之间的关系研究对图像重建具有重要的实际意义。使用商业有限元仿真软件COMSOL多发性,设计了一种基于有限元的二维仿真模型,研究了光声信号的光谱特性与吸收器的形状和尺寸之间的关系。在这项研究中,该模型由三部分组成:1)水层; 2)短脉冲激光源(波长为840nm); 3)胃肿瘤组织。激光点源位于上水层的中间。通过求解扩散方程,模拟光在水层中的传播。通过求解生物液体方程来获得生物组织中的温度变化。当吸收器被高斯脉冲照射时,由于极短的时间,吸收器可以被视为吸收能量之后的绝热膨胀,从而产生超声波。使用有限元分析方法,光声成像的复杂情况被转换为多个物理场的耦合和部分微分方程的数值计算以获得光声信号。拟合仿真结果表明光声信号的光谱特性定期改变吸收器的尺寸。本文获得的吸收器的尺寸具有与光谱截距的功率功能关系。尺寸越大,光谱截距越大,而且增长速率随着尺寸的增加而增加。吸收器的大小和光谱斜率也具有功率函数关系。大谱的斜率较小,随着尺寸的增加而变化的变化率降低。同时,分析不同形状的吸收器的光声光谱还表明,不同形状的吸收器具有它们自己的特性。该研究有助于了解吸收器的光谱特性和形状和尺寸之间的关系,对图像重建具有一定的理论指导意义。

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