Conjugate Substitution of α-(Halomethyl)acrylate: A Facile, Versatile, and Convenient Reaction for Poly (conjugated ester) Synthesis

摘要

Introduction: α-(Halomethyl)acrylate includes two characteristic structures, i.e. an acryloyl group and an allyl halide skeleton. Once the former accepts the nucleophilic attack at the vinylidene group, the reformation of double bond and the subsequent elimination of halogen atom in the allyl position follows; overall, so-called conjugate substitution through addition-elimination (Sn2') mechanism. Conjugate substitution proceeds quantitatively with a variety of nucleophile under ambient condition even in nonpolar solvents. Inspired from these useful features, polycondensation based on conjugate substitution was investigated.