Real-time detection of neuronal activity induced by time-varying magnetic field or electric field exposure in in vitro

摘要

Rat primary cortical neuron culture and human iPS cell-derived neurons were used to investigate threshold of magnetic/electric stimulation of nerve cells in in vitro. Originally developed live cell imaging system for real-time detection of neuronal activity without disturbing by interference of magnetic field was used. In magnetic field exposure experiment, it seemed that response of neuron cell that synchronized with magnetic field in some cases but observed neuronal activity was not necessarily synchronized with magnetic field exposure. Improvement of cell direction, orientation of neuronal network and other factors may need to observe neuronal cell response certainly. Further results will be presented in the Congress.