POSACONAZOLE PHARMACOKINETICS IN CATS AFTER ORAL AND IV ADMINISTRATION

摘要

Posaconazole is the most active available azole antifungal drug, but absorption and pharmacokinetics are not available to guide dosing regimens in cats. The purpose of this study was to determine pharmacokinetics of oral suspension and IV formulations of posaconazole in cats to determine the feasibility of oral administration for treatment of fungal infections.