Poly(3, 4-Ethylenedioxythiophene) Derivatives with Electrochemical Chiral Sensor for 3, 4-Dihydroxyphenylalanine Discrimination

摘要

Two chiral Poly(3, 4-ethylenedioxythiophene) (PEDOT) derivatives, Poly(N-(tert-butoxycarbonyl)-L-phenylalayl (3, 4-ethylenedioxythiophene-2'-yl)methylamide) (PEDOT-Boc-Leu) and Poly(L-phenylalayl (3, 4-ethylenedioxythiophene-2'-yl)methylamide) (PEDOT-Leu) modified electrodes were used to recognize 3, 4-dihydroxyphenylalanine (DOPA) enantiomers by square wave voltammetry (SWV) and cyclic voltammetry (CV) in sulphuric acid solution. It was amazing that the SWV peak currents of enantiomers were found to be quite different and hence the enantiomers could be successfully recognized. However, no obvious difference was observed by the method of CV. Satisfactory results implied that the obtained polymer films could play crucial roles in the development of practical value and analytical application prospects.