Characterization of a Multi-Functional Tetronic Surgical Adhesive Containing Chitosan for Soft Tissue Applications

摘要

A multi-functional Tetronic adhesive was developed and characterized for its ability to stop blood loss from punctured liver. By incorporating chitosan within the bi-functional Tetronic adhesive, we not only added hemostatic functionality, but also improved the handling time for application of the hydrogel adhesive. However, further testing, especially in vivo, is needed to the determine cytotoxicity and biocompatibility of our multi-functional Tetronic tissue adhesive.