Fluorenylmethyloxycarbonyl-based Peptide-Chitosan hybrid Scaffolds for Potential Applications in Cartilage Tissue Regeneration

摘要

A new nanoscale biomimetic peptide-based hydrogel nanoscaffold was prepared by the layer-by-layer assembly method. The interactions of the scaffolds with chondrocyte cells was studied. The nanoscaffolds exhibited biocompatibility, induced proliferation of chondrocyte cells and promoted chondrogenesis. Such nanoscaffolds may have potential applications in cartilage tissue regeneration therapeutics.