Reconfigurable Substrate Topography for Tracking Cell Dynamics

摘要

Recognizable substrate is a tool for elucidating cell-topography interactions. Here, we fabricate the topographic substrate that can be controlled using small strain for limiting external stimuli. The substrate presents consistent buckling patterns that benefit in measuring cell responses, such as cell morphodynamics. This technique can also measure or control cell migration and differentiation that could be used in various biomedical applications.