Poly(ethylene glycol) diacrylate (PEGDA) multiluminal scaffold for spinal cord repair functionalized with layer-by-layer controlled protein release

摘要

Progress towards clinically-relevant NGS has been made. The integration of degradable hydrogels (PEGDA-RGD) with improved compatibility compared to previously used agarose hydrogel scaffolds was demonstrated. The LbL process is also compatible with PEGDA-RGD hydrogel, capable of protein release above required therapeutic dosage. In vivo testing indicated that the PEGDA scaffolds show promise toward establishing therapies for spinal cord injuries.