Current Vaccinology Considerations in North American Foreign Animal Disease Events - Implications for Foot-and-Mouth Disease (FMD) Preparedness and Response

摘要

The importance of the disease under consideration relates to many factors. FMD is among the diseases of highest concern."... Its importance to mankind is confirmed by the fact that FMD virus (FMDV) was the first animal virus discovered...." FMD was one of the first diseases for which vaccines were developed. Over time, we have realized "... vaccines are very useful as part of an eradication campaign in countries where FMDV is enzootic... these vaccines are not ideally suited to control outbreaks in disease-free countries..." Thus, there is a need for new FMD vaccines (Mason and Grubman).