Magnesium Substitution in Hydroxyapatite Synthesized by Sol-Gel Method

摘要

The ionic substitutions have been proposed as a tool to improve the biological performance of hydroxyapatite (HAp) based materials. In the present work, the systems of Ca_(10-x)Mg_x(PO_4)_6(OH)_2 (MgHAp, x = 0, 1, 2, and 3) were successfully synthesized by sol-gel method. To obtain nanocrystalline of MgHAp, the prepared precursors were calcined in air at 600°C for 2 h. The samples were characterized by X-ray diffraction (XRD) and transmission electron microscope (TEM) observation. The XRD results confirm the formation of pure phase of HAp with the lattice parameter a in the range of 0.9417-0.9479 nm and c of 0.6841-0.6919 nm. The crystallite sizes of the powder are found to be 35-46 nm as evaluated by the XRD line broadening method. The morphology of the samples are spherical shape of diameter less than 100 nm as evaluated by TEM. The corresponding selected area electron diffraction (SAED) analysis further confirms the formation of hexagonal structure of HAp.