Automated Readout of a SERS Lateral Flow Assay

摘要

The coupling of Lateral Flow Assays (LFA) to Surface Enhanced Raman Scattering (SERS) readout is promising to obtain field biosensors with exquisite sensitivity. For Point of Care (POC) applications, however, the operation of such a SERS-LFA sensor needs to be automated. We developed an acquisition protocol together with a procedure for processing the Raman spectra to address this point. We describe this method and present some results obtained on Ovalbumin as a model target.