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Volumetric flow rate in simulations of microfluidic devices

机译:微流体装置模拟中的体积流速

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In this work, we examine the volumetric flow rate of microfluidic devices. The volumetric flow rate is a parameter which is necessary to correctly set up a simulation of a real device and to check the conformity of a simulation and a laboratory experiments [1]. Instead of defining the volumetric rate at the beginning as a simulation parameter, a parameter of external force is set. The proposed hypothesis is that for a fixed set of other parameters (topology, viscosity of the liquid, ...) the volumetric flow rate is linearly dependent on external force in typical ranges of fluid velocity used in our simulations. To confirm this linearity hypothesis and to find numerical limits of this approach, we test several values of the external force parameter. The tests are designed for three different topologies of simulation box and for various haematocrits. The topologies of the microfluidic devices are inspired by existing laboratory experiments [3-6]. The linear relationship between the external force and the volumetric flow rate is verified in orders of magnitudes similar to the values obtained from laboratory experiments.
机译:在这项工作中,我们检查了微流体装置的体积流量。体积流量是正确设置真实装置的模拟所必需的参数,并检查模拟和实验室实验的符合性[1]。而不是在开始时将体积速率定义为仿真参数,因此设置了外力的参数。所提出的假设是,对于固定的其他参数(拓扑,液体的胶质,...),体积流速是线性的,其依赖于我们模拟中使用的典型流体速度范围内的外力。要确认此线性假设并找到此方法的数值限制,我们测试了外力参数的几个值。测试专为三种不同拓扑结构的仿真盒和各种血上设计。微流体装置的拓扑通过现有的实验室实验启发[3-6]。外力与体积流速之间的线性关系以类似于从实验室实验所获得的值的阶数验证。

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