Production of Carp Immunoglobulin-M Exposed with Whole Protein from Myxobolus koi Spore through Feed as an Immunostimulant

摘要

Carp production in Indonesia in 2010-2015 has increased an average of 14.44%, a low average increase in production when compared with other main commodities such as shrimp, tilapia, catfish and others. One of the causes of the low average increase in production is the presence of disease attacks in some carp central production. One of the natural ingredients that can be used to control the body system against the disease is the whole protein from Myxobolus koi spore. The aim of this study was to analyze the effect of whole protein from Myxobolus koi spore on carp (Cyprinus carpio L.) through feed on increasing Immunoglobulin M (IgM) value in blood. This research was conducted by Randomized Complete Design with 5 replications. This study uses three kinds of treatment, control (100% commercial feed, 100% artificial feed and artificial feed + Immunostimulants (whole protein from Myxobolus koi spore as 1μg protein/gram fish) + adhesive Boster Progol. The immunostimulan dose is of the whole protein from Myxobolus koi spores with a dose of 1μg protein/gram fish + adhesive Boster Progol with a volume of 5 ml/kg of feed. First step is identification of the pathogens that attack the carp before (first day) and after a given treatment (day 28). The results show that whole protein from Myxobolus koi spores given in feed as the immunostimulant have a significantly different effect (p <0.05) on the number of pathogens attack and carp (Cyprinus carpio L.) IgM concentration. The immunostimulant can boost the immune system by increasing the IgM concentration of day 7 (1463,566μg/ml), day 14 (2189, 368μg/ml) and day 28 (1939, 087μg/ml) formed by proliferation of lymphocyte B and 99% survival rate.